LARGE-SCALE ANTIBODY IMMUNE RESPONSE MAPPING OF SPLENIC B CELLS AND BONE MARROW PLASMA CELLS IN A TRANSGENIC MOUSE MODEL

Large-scale antibody immune response mapping of splenic B cells and bone marrow plasma cells in a transgenic mouse model

Molecular characterization of antibody immunity and human antibody discovery is mainly carried out using peripheral memory B cells, and occasionally plasmablasts, that express B cell receptors (BCRs) on their cell surface.Despite the importance of plasma cells (PCs) as the dominant source of circulating antibodies in serum, PCs are rarely utilized

read more

Temporal Profiling of the Cortical Synaptic Mitochondrial Proteome Identifies Ageing Associated Regulators of Stability

Synapses are particularly susceptible to the effects of advancing age, and mitochondria have long been implicated as organelles contributing to this compartmental vulnerability.Despite this, the gruvi golden lager mitochondrial molecular cascades promoting age-dependent synaptic demise remain to be elucidated.Here, we sought to examine how the syna

read more

Analyzing a memoir of disability: Utilizing a group writing assignment to increase applicability and comprehension of course material

"Analyzing a Memoir of Disability" is a semester-long project that promotes learning about disability and culture through group reading and writing about a single memoir.Students in an Introduction to Rehabilitation and Human Services course completed the gel bottle cashmere a textual analysis by using a memoir and course textbook to contextualize

read more


Clinical potential of mechlorethamine gel for the topical treatment of mycosis fungoides-type cutaneous T-cell lymphoma: a review on current efficacy and safety data

Kendall Liner,1 Celeste Brown,2 Laura Y McGirt3 1Division of Dermatology, Medical College of Georgia at Augusta Health, Augusta, GA, read more USA; 2School of Medicine, University of North Carolina at Chapel Hill, Carolinas Medical Center, Charlotte, NC, USA; 3Department of Hematology/Oncology, Levine Cancer Institute, Carolinas Medical Center, Cha

read more